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Example: Chronic drinking promotes fatty liver because metabolism favors lipogenesis

Dinner: Lean beef (B6 per 100 g: 0.5 mg, B12 per 100 g: 2.6 mcg) Beans/lentils (~50% RDA folate) Broccoli (27% RDA folate) Olive oil (Moroccan olive oil is highly recommended for its high hydroxytyrosol content) Lean beef is an excellent source of protein, iron, Vitamin B12, zinc, selenium, niacin, and phosphorus

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Consequently, we relied on functional studies in our genetically engineered mouse model of RMC, which recapitulated the hyperprogression observed in humans and allowed us to interrogate the specific role of IFNIFNGR1p300 signaling